Vidan’s Pre-filled Reagent Kits makes it easy to load directly onto the ARCHITECTTM chemistry systems

Vidan’s Pre-filled Reagent Kits makes it easy to load directly onto the ARCHITECTTM chemistry systems

Key Benefits of β-Hydroxybutyrate 21FS

Excellent precision

  • The Vidan Diagnostics β-Hydroxybutyrate 21FS assay showed a precision of less than 3.2% CV
  • Exceptional correlation with standard methods
  • The Vidan Diagnostics methodology was compared against another commercially available method and the Vidan β-Hydroxybutyrate 21FS assay showed a correlation coefficient of r=0.999

Wide measuring range

  • The normal range for β-Hydroxybutyrate 21FS in serum is 0.02 – 0.27 mmol/L. The Vidan Diagnostics β-Hydroxybutyrate 21FS assay can comfortably detect levels outside of its normal range having linearity up to 6.0 mmol/L

Features of the Abbott ARCHITECT™ β-Hydroxybutyrate 21FS reagent

  • Next Generation Enzymatic Method
  • Liquid-stable & Ready-to-use Reagents
  • Pre-filled Reagent Kits for Abbott ARCHITECT™
  • 10 Weeks Reagent On-board Stability
  • 10 Weeks Calibration Stability

Architect™ 20mL Reagent Cartridge Adapters

Instrument Specific Applications (ISA) are available for a wide range of clinical chemistry analyzers. Contact us to inquire about your specific analyzer.

What is the β-Hydroxybutyrate 21FS assay used for?

What is β-Hydroxybutyrate?

β-Hydroxybutyrate is the major ketone body produced in the liver due to the oxidation of fatty acids. It is transported in the blood to peripheral tissues and used as an energy source. The nitroprusside method of ketone detection, used in qualitative dipstick tests, detects acetone and acetoacetate, but it does not detect β-Hydroxybutyrate. The nitroprusside method is also prone to interferences from sulfhydryl medications and the levels of ketones present in urine often lag between 2 to 4 hours behind the levels in blood.

What is the β-Hydroxybutyrate used for?

The Vidan Diagnostics β-Hydroxybutyrate 21FS assay is used for the quantitative in vitro determination of β-Hydroxybutyrate in serum or plasma. Vidan Diagnostics test for β-Hydroxybutyrate as opposed to acetone or acetoacetate because β-Hydroxybutyrate is a more sensitive biomarker of ketosis as the β-Hydroxybutyrate levels are more elevated compared to acetone and acetoacetate. β-Hydroxybutyrate is also the most stable ketone body (7 days at +4⁰C) – Acetone and acetoacetate are unstable, and so serious errors can arise if analysis is delayed. The Vidan Diagnostics β-Hydroxybutyrate assay can be used for the detection of ketosis is important in several conditions:

  • Diabetic ketosis
  • Alcoholic ketosis
  • Severe injury, illness or sepsis
  • Dieting
  • Childhood epilepsy
  • Ketotic hypoglycemia

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